Browsing Experimentally Confirmed database

Result: Your query found 7 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
qacH/qacI
  • BacMet ID: BAC0326
  • Code for: Efflux
  • Family: Small multidrug resistance (SMR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: only gram +ve, Staphylococcus aureus
  • Location: Plasmid pST2H6 ( Staphylococcus saprophyticus)
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Proflavin [class: Acridine]
  • Description: Quaternary ammonium compound-resistance protein qacH (also known as qacI), Multidrug exporter. Is implicated for the resistance to bacteriocidal quaternary ammonium compounds.
  • Length (amino acid): 107
  • Reference: Heir et al. 1998; Pubmed- 9631545

  • Similar resistance genes in 'BacMet Predicted database'
    smeD
  • BacMet ID: BAC0358
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Stenotrophomonas maltophilia
  • Location: Chromosome
  • Compound: Triclosan [class: Phenolic compounds], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Crystal Violet [class: Triarylmethane], Ethidium Bromide [class: Phenanthridine], Proflavin [class: Acridine], SDS
  • Description: Membrane fusion protein of RND family multidrug efflux pump smeD; part of the smeDEF efflus system. It confers resisance to a wide range of antibiotics.
  • Length (amino acid): 394
  • Reference: Sanchez et al. 2005; Pubmed- 15673767, Alonso et al. 2000; Pubmed- 11036026, Zhang et al. 2001, Pubmed- 11709330

  • Similar resistance genes in 'BacMet Predicted database'
    smeE
  • BacMet ID: BAC0359
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Stenotrophomonas maltophilia
  • Location: Chromosome
  • Compound: Triclosan [class: Phenolic compounds], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Crystal Violet [class: Triarylmethane], Ethidium Bromide [class: Phenanthridine], Proflavin [class: Acridine], SDS
  • Description: RND efflux system, inner membrane transporter┬ásmeE; part of the smeDEF efflus system. It confers resisance to a wide range of antibiotics.
  • Length (amino acid): 1040
  • Reference: Sanchez et al. 2005; Pubmed- 15673767, Alonso et al. 2000; Pubmed- 11036026, Zhang et al. 2001, Pubmed- 11709330

  • Similar resistance genes in 'BacMet Predicted database'
    smeF
  • BacMet ID: BAC0360
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Stenotrophomonas maltophilia
  • Location: Chromosome
  • Compound: Triclosan [class: Phenolic compounds], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Crystal Violet [class: Triarylmethane], Ethidium Bromide [class: Phenanthridine], Proflavin [class: Acridine], SDS
  • Description: Multidrug resistance outer membrane protein smeF; part of the smeDEF efflus system. It confers resisance to a wide range of antibiotics.
  • Length (amino acid): 466
  • Reference: Sanchez et al. 2005; Pubmed- 15673767, Alonso et al. 2000; Pubmed- 11036026, Zhang et al. 2001, Pubmed- 11709330

  • Similar resistance genes in 'BacMet Predicted database'
    tehA
  • BacMet ID: BAC0384
  • Code for: Membrane Transporter
  • Family: Tellurite-resistance/dicarboxylate transporter (TDT) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tellurium (Te), Proflavin [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat]
  • Description: Tellurite resistance protein TehA; The gene encodes an integral membrane protein. Responsible for potassium tellurite resistance when present in high copy number. Ion channel involved in potassium tellurite resistance, otherwise phenotypically silent
  • Length (amino acid): 330
  • Reference: Walter et al 1991; Pubmed- 2060788, Taylor et al. 1994; Pubmed- 8169225, Turner et al. 1997; Pubmed- 9021204

  • Similar resistance genes in 'BacMet Predicted database'
    tehB
  • BacMet ID: BAC0385
  • Code for: Enzyme
  • Family: TehB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tellurium (Te), Proflavin [class: Acridine]
  • Description: S-adenosyl-L-methionine dependent methyltransferase tehB that catalyzes the methylation of tellurite and is responsible for tellurite resistance when present in high copy number. Can also methylate selenite and selenium dioxide. Is thus able to detoxify different chalcogens. Can not methylate arsenic compounds
  • Length (amino acid): 197
  • Reference: Walter et al 1991; Pubmed- 2060788, Taylor et al. 1994; Pubmed- 8169225

  • Similar resistance genes in 'BacMet Predicted database'
    tolC
  • BacMet ID: BAC0393
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Phenol [class: Phenolic compounds], Triclosan [class: Phenolic compounds], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Taurodeoxycholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Proflavin [class: Acridine], Acriflavine [class: Acridine], Ethidium Bromide [class: Phenanthridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Rhodamine 6G [class: Xanthene], Tetraphenylarsonium (TPA) [class: Quaternary Ammonium Compounds (QACs)], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Plumbagin [class: Naphthoquinone]
  • Description: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria. Required for acrAB, mar efflux pumps to act as multidrug efflux pump.
  • Length (amino acid): 493
  • Reference: Hackett et al. 1983; Pubmed- 6312426, Fralick et al. 1996; Pubmed- 8824631, Sulavik et al. 2001; Pubmed- 11257026

  • Similar resistance genes in 'BacMet Predicted database'

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