sugE | BacMet ID: BAC0378Code for: Efflux
Family: Small multidrug resistance (SMR) family (SugE subfamily)Sequence: FASTA
Cross-database information: Link
Organism: only gram -ve, Escherichia coliLocation: Plasmid IncN p541 (Escherichia coli), Plasmid pIW759 (Salmonella typhimurium)
Compound: Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], and Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]Description: Quaternary ammonium compound-resistance protein sugE, Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Unlike the other members of the SMR family, SugE exhibits a narrow specificity for a very specific class of compounds.
Length (amino acid): 105
Reference: Chung et al. 2002; Pubmed- 11948170, He et al. 2011; Pubmed- 21576447
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Similar resistance genes in 'BacMet Predicted database' |