| perR |
BacMet ID: BAC0310Code for: Regulator
Family: Fur familySequence: FASTA
Cross-database information: Link
Organism: Staphylococcus aureus (strain NCTC 8325)Location: Chromosome
Compound: Hydrogen Peroxide (H2O2) [class: Peroxides]Description: Peroxide-responsive repressor PerR; Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. Regulates expression of genes encoding antioxidant proteins, such as katA, ahpCF, bcp and trxB. Also regulates expression of the iron-storage protein ftn, the ferritin-like protein mrgA, the ferric uptake regulator fur, the manganese transporter operon mntABC, and its own expression. May act as a hydrogen peroxide and organic hydroperoxide sensor. Required for full virulence in a murine skin abscess model of infection
Length (amino acid): 148
Reference: Horsburgh et al. 2001; Pubmed- 11349039
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Similar resistance genes in 'BacMet Predicted database' |
