Gene_name | Experimentally Verified Resistance Gene Information | Predicted Resistance Gene Information |
ttgA | BacMet ID: BAC0404Code for:
EffluxFamily: RND superfamily, MFP familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
ChromosomeCompound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: Toluene efflux pump periplasmic linker protein TtgA; The periplasmic linker protein component of a constitutive organic solvent efflux system ttgABC. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also Exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.Length (amino acid):
384Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |
ttgB | BacMet ID: BAC0405Code for:
EffluxFamily: RND superfamily, AcrB/AcrD/AcrF familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
ChromosomeCompound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: The inner membrane transporter component, ttgB of a constitutive organic solvent efflux system ttgABC. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also Exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.Length (amino acid):
1050Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |
ttgC | BacMet ID: BAC0406Code for:
EffluxFamily: RND Superfamily, OMP familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
ChromosomeCompound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: The outer membrane component ttgC of a constitutive organic solvent efflux system ttgABC. Is involved in Export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.Length (amino acid):
484Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |
ttgG | BacMet ID: BAC0410Code for:
EffluxFamily: RND superfamily, MFP familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: The periplasmic linker component ttgG, of an organic solvent efflux pump ttgGHI. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can Export AMP and some antibiotics.Length (amino acid):
391Reference: Rojas et al. 2001; Pubmed- 11395460, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |
ttgH | BacMet ID: BAC0411Code for:
EffluxFamily: RND superfamily, AcrB/AcrD/AcrF familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: The inner membrane transporter component, ttgH of an organic solvent efflux pump ttgGHI. Involved in Export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can Export AMP and some antibioticsLength (amino acid):
1049Reference: Rojas et al. 2001; Pubmed- 11395460, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |
ttgI | BacMet ID: BAC0412Code for:
EffluxFamily: RND Superfamily, OMP familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: The outer membrane component, ttgI of an organic solvent efflux pump ttgGHI. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can Export AMP and some antibiotics.Length (amino acid):
470Reference: Rojas et al. 2001; Pubmed- 11395460, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |
ttgR | BacMet ID: BAC0413Code for:
RegulatorFamily: Contains 1 HTH tetR-type DNA-binding domainSequence: FASTACross-database IDs: LinkOrganism: Pseudomonas putida (Arthrobacter siderocapsulatus)Location:
ChromosomeCompound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]Description: Toluene efflux pump ttgABC operon repressor ttgR; Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.Length (amino acid):
210Reference: Duque et al. 2001; Pubmed- 11251828, Teran et al. 2003; Pubmed- 14506010, Fernandes et al. 2003; Pubmed- 13678823
| Similar
resistance genes in 'BacMet Predicted database' |