Browsing Experimentally Confirmed database

Result: Your query found 12 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
abeM
  • BacMet ID: BAC0001
  • Code for: Efflux
  • Family: MATE family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumanni
  • Location: Chromosome
  • Compound: 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Triclosan [class: Phenolic compounds], Acriflavine [class: Acridine], Hoechst 33342 [class: Bisbenzimide], Rhodamine 6G [class: Xanthene], Ethidium Bromide [class: Phenanthridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: H-coupled multidrug efflux pump. Confers resistance to Antibiotics such as quinolones and aminoglycosides and antibacterial biocides such as dyes, QACs.
  • Length (amino acid): 448
  • Reference: Su et al. 2005; Pubmed- 16189122

  • Similar resistance genes in 'BacMet Predicted database'
    hmrM
  • BacMet ID: BAC0189
  • Code for: Efflux
  • Family: MATE family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Haemophilus influenzae
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Ethidium Bromide [class: Phenanthridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Hoechst 33342 [class: Bisbenzimide]
  • Description: Multidrug efflux pump that functions as a Na+/drug antiporter. Confers resistance to norfloxacin, Acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate
  • Length (amino acid): 464
  • Reference: Xu et al. 2003; Pubmed- 14695443

  • Similar resistance genes in 'BacMet Predicted database'
    kmrA
  • BacMet ID: BAC0493
  • Code for: Efflux
  • Family: MFS superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Hoechst 33342 [class: Bisbenzimide], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: It can confer resistance to Antibiotics such as kanamycin, gentamycin, erythromycin etc.
  • Length (amino acid): 499
  • Reference: Ogawa et al. 2006; Pubmed- 16508165

  • Similar resistance genes in 'BacMet Predicted database'
    mdeA
  • BacMet ID: BAC0207
  • Code for: Enzyme
  • Family: Trans-sulfuration enzymes family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide], Ethidium Bromide [class: Phenanthridine], Rhodamine 6G [class: Xanthene], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Pentamidine [class: Diamidine], Pyronin Y [class: Xanthene]
  • Description: Methionine gamma-lyase (MdeA)
  • Length (amino acid): 398
  • Reference: Huang et al. 2004; Pubmed- 14982783, Yamada et al. 2006; Pubmed- 16595922, Huet et al. 2008; Pubmed- 18832320

  • Similar resistance genes in 'BacMet Predicted database'
    smdA
  • BacMet ID: BAC0353
  • Code for: Efflux
  • Family: ABC superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Serratia marcescens
  • Location: Chromosome
  • Compound: 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Hoechst 33342 [class: Bisbenzimide]
  • Description: Multidrug efflux pump SmdA
  • Length (amino acid): 591
  • Reference: Matsuo et al. 2008; Pubmed- 18024518

  • Similar resistance genes in 'BacMet Predicted database'
    smdB
  • BacMet ID: BAC0354
  • Code for: Efflux
  • Family: ABC superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Serratia marcescens
  • Location: Chromosome
  • Compound: 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Hoechst 33342 [class: Bisbenzimide]
  • Description: Multidrug efflux pump SmdB
  • Length (amino acid): 592
  • Reference: Matsuo et al. 2008; Pubmed- 18024518

  • Similar resistance genes in 'BacMet Predicted database'
    smvA/emrB
  • BacMet ID: BAC0367
  • Code for: Efflux
  • Family: Major facilitator superfamily (MFS),¬†TCR/tet family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Salmonella typhimurium
  • Location: Chromosome
  • Compound: Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide], Ethidium Bromide [class: Phenanthridine], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine]
  • Description: Methyl viologen resistance protein SmvA, Major efflux pump for Acriflavine and other quaternary ammonium compounds (QACs). Also required for resistance to methyl viologen, Mutants show increased sensitivity to methyl viologen and Acriflavine.
  • Length (amino acid): 495
  • Reference: Santiviago et al. 2002; Pubmed- 12410826, Hongo et al. 1994; Pubmed- 7926834, Ogawa et al. 2006; Pubmed- 16508165

  • Similar resistance genes in 'BacMet Predicted database'
    vcmA
  • BacMet ID: BAC0422
  • Code for: Efflux
  • Family: MATE family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio chloerae
  • Location: Chromosome
  • Compound: Ethidium Bromide [class: Phenanthridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Hoechst 33342 [class: Bisbenzimide], Acriflavine [class: Acridine]
  • Description: Multidrug efflux pump vcmA that functions as a Na+/drug antiporter. Confers resistance to norfloxacin, ciprofloxacin, ofloxacin, daunomycin, doxorubicin, streptomycin, kanamycin, ethidium bromide, 4',6'-diamidino-2-phenylindole and Acriflavine
  • Length (amino acid): 457
  • Reference: Huda et al. 2001; Punmed: 11583854

  • Similar resistance genes in 'BacMet Predicted database'
    vcrM
  • BacMet ID: BAC0423
  • Code for: Efflux
  • Family: MATE family, DinF-subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio cholerae non-O1
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Hoechst 33342 [class: Bisbenzimide], Rhodamine 6G [class: Xanthene], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine]
  • Description: A Na+/drug antiporter-type multidrug efflux pump vcrM
  • Length (amino acid): 445
  • Reference: Huda et al. 2002; Pubmed- 12906102

  • Similar resistance genes in 'BacMet Predicted database'
    vmeC
  • BacMet ID: BAC0510
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Rhodamine 6G [class: Xanthene], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide]
  • Description: VmeCD uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 368
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeD
  • BacMet ID: BAC0511
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Rhodamine 6G [class: Xanthene], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide]
  • Description: VmeCD uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 1040
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vpoC
  • BacMet ID: BAC0516
  • Code for: Efflux
  • Family: RND superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Ethidium Bromide [class: Phenanthridine], Rhodamine 6G [class: Xanthene], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid]
  • Description: Homologue of E. coli TolC outer membrane protein, vpoC.
  • Length (amino acid): 442
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'

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