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Browsing Experimentally Confirmed database

Result: Your query found 6 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_name	Experimentally Verified Resistance Gene Information	Predicted Resistance Gene Information
emrA	BacMet ID: BAC0147 Code for: Efflux Family: Membrane Fusion Protein (MFP) Sequence: FASTA Cross-database IDs: Link Organism: Escherichia coli (strain K12) Location: Chromosome Compound: Phenylmercury Acetate [class: Organo-mercury], 2-Chlorophenylhydrazine [class: Hydrazine], Carbonylcyanide m-chlorophenyl hydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide] Description: The emr locus confers resistance to substances of high hydrophobicity. EmrA probably participate in a transport system to extrude toxins and drugs from the cell. Length (amino acid): 390 Reference: Lomovskaya et al. 1992; Pubmed- 1409590	Similar resistance genes in 'BacMet Predicted database'
emrAsm	BacMet ID: BAC0499 Code for: Efflux Family: MFS superfamily Sequence: FASTA Cross-database IDs: Link Organism: Stenotrophomonas maltophilia (strain K279a) Location: Chromosome Compound: Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide] Description: Part of EmrCABsm efflux pump which is a similar pump found in E. coli (EmrCAB) with below 50% amino acid identities. EmrCsm and EmrAB are essential for the function of the EmrCABsm pump. EmrCABsm pump may have a physiological role in evading naturally produced molecules from the environment or host-derived compounds, rather than in antimicrobial extrusion, allowing S. maltophilia to survive in its ecological niche. It can confer resistance to hydrophobic antibiotics nalidixic acid and erythromycin. Length (amino acid): 393 Reference: Huang et al. 2013; Pubmed- 23794602	Similar resistance genes in 'BacMet Predicted database'
emrBsm	BacMet ID: BAC0500 Code for: Efflux Family: MFS superfamily Sequence: FASTA Cross-database IDs: Link Organism: Stenotrophomonas maltophilia (strain K279a) Location: Chromosome Compound: Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide] Description: Part of EmrCABsm efflux pump which is a similar pump found in E. coli (EmrCAB) with below 50% amino acid identities. EmrCsm and EmrAB are essential for the function of the EmrCABsm pump. EmrCABsm pump may have a physiological role in evading naturally produced molecules from the environment or host-derived compounds, rather than in antimicrobial extrusion, allowing S. maltophilia to survive in its ecological niche. It can confer resistance to hydrophobic antibiotics nalidixic acid and erythromycin. Length (amino acid): 528 Reference: Huang et al. 2013; Pubmed- 23794602	Similar resistance genes in 'BacMet Predicted database'
emrCsm	BacMet ID: BAC0501 Code for: Efflux Family: MFS superfamily Sequence: FASTA Cross-database IDs: Link Organism: Stenotrophomonas maltophilia (strain K279a) Location: Chromosome Compound: Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide] Description: Outer membrane protein EmrCsm. Part of EmrCABsm efflux pump which is a similar pump found in E. coli (EmrCAB) with below 50% amino acid identities. EmrCsm and EmrAB are essential for the function of the EmrCABsm pump. EmrCABsm pump may have a physiological role in evading naturally produced molecules from the environment or host-derived compounds, rather than in antimicrobial extrusion, allowing S. maltophilia to survive in its ecological niche. It can confer resistance to hydrophobic antibiotics nalidixic acid and erythromycin. Length (amino acid): 497 Reference: Huang et al. 2013; Pubmed- 23794602	Similar resistance genes in 'BacMet Predicted database'
emrRsm	BacMet ID: BAC0502 Code for: Regulator Family: MarR family Sequence: FASTA Cross-database IDs: Link Organism: Stenotrophomonas maltophilia (strain K279a) Location: Chromosome Compound: Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide] Description: EmrRCABsm operon is negatively regulated by a MarR-type regulator EmrRsm. Length (amino acid): 147 Reference: Huang et al. 2013; Pubmed- 23794602	Similar resistance genes in 'BacMet Predicted database'
tolCsm	BacMet ID: BAC0507 Code for: Efflux Family: RND superfamily, OMP family Sequence: FASTA Cross-database IDs: Link Organism: Stenotrophomonas maltophilia (strain K279a) Location: Chromosome Compound: Acriflavine [class: Acridine], Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Crystal Violet [class: Triarylmethane], Methyl Viologen [class: Paraquat], Plumbagin [class: Naphthoquinone], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide], Menadione [class: Naphthoquinone] Description: Outer membrane protein. pcm and tolCsm genes form an operon. A significant feature of TolCsm different from that of other tolC homologues of Enterobacteriaceae is that tolCsm is not transcribed alone, but is transcribed with the pcm gene. Length (amino acid): 452 Reference: Huang et al. 2013; Pubmed- 23629016	Similar resistance genes in 'BacMet Predicted database'

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