Browsing Experimentally Confirmed database

Result: Your query found 9 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
srpA
  • BacMet ID: BAC0372
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate]
  • Description: Solvent-resistant efflux pump periplasmic linker SrpA; a component of an organic solvent efflux pump srpABC. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been postulated to depend on the operon Expression level.
  • Length (amino acid): 382
  • Reference: Kieboom et al. 1998; Pubmed- 9417051, Kieboom eta l. 1998; Pubmed- 9852029, Kim et al. 1998; Pubmed- 9658016

    		• Similar resistance genes in 'BacMet Predicted database'
    srpB
  • BacMet ID: BAC0373
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate]
  • Description: Solvent-resistant pump membrane transporter SrpB; The inner membrane transporter component of an organic solvent efflux pump srpABC. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been postulated to depend on the operon expression level.
  • Length (amino acid): 1049
  • Reference: Kieboom et al. 1998; Pubmed- 9417051, Kieboom eta l. 1998; Pubmed- 9852029, Kim et al. 1998; Pubmed- 9658016

    		• Similar resistance genes in 'BacMet Predicted database'
    srpC
  • BacMet ID: BAC0374
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate]
  • Description: Solvent-resistant efflux pump outer membrane protein SrpC; The outer membrane component of an organic solvent efflux pump srpABC. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been postulated to depend on the operon expression level.
  • Length (amino acid): 470
  • Reference: Kieboom et al. 1998; Pubmed- 9417051, Kieboom eta l. 1998; Pubmed- 9852029, Kim et al. 1998; Pubmed- 9658016

    		• Similar resistance genes in 'BacMet Predicted database'
    srpR
  • BacMet ID: BAC0375
  • Code for: Regulator
  • Family: Contains 1 HTH tetR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate]
  • Description: Solvent efflux pump srpABC operon corepressor SrpR; In conjunction with SrpS represses the srpABC operon.
  • Length (amino acid): 213
  • Reference: Sun et al. 2011; Pubmed- 21441510

    		• Similar resistance genes in 'BacMet Predicted database'
    srpS
  • BacMet ID: BAC0376
  • Code for: Regulator
  • Family: Contains 1 HTH iclR-type DNA-binding domain, 1 iclR-ED (iclR effector binding) domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate]
  • Description: Solvent efflux pump srpABC operon corepressor SrpS; In conjunction with SrpR represses the srpABC operon.
  • Length (amino acid): 259
  • Reference: Sun et al. 2011; Pubmed- 21441510

    		• Similar resistance genes in 'BacMet Predicted database'
    ttgA
  • BacMet ID: BAC0404
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: Toluene efflux pump periplasmic linker protein TtgA; The periplasmic linker protein component of a constitutive organic solvent efflux system ttgABC. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also Exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
  • Length (amino acid): 384
  • Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823

    		• Similar resistance genes in 'BacMet Predicted database'
    ttgB
  • BacMet ID: BAC0405
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The inner membrane transporter component, ttgB of a constitutive organic solvent efflux system ttgABC. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also Exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
  • Length (amino acid): 1050
  • Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823

    		• Similar resistance genes in 'BacMet Predicted database'
    ttgC
  • BacMet ID: BAC0406
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The outer membrane component ttgC of a constitutive organic solvent efflux system ttgABC. Is involved in Export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
  • Length (amino acid): 484
  • Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823

    		• Similar resistance genes in 'BacMet Predicted database'
    ttgR
  • BacMet ID: BAC0413
  • Code for: Regulator
  • Family: Contains 1 HTH tetR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: Toluene efflux pump ttgABC operon repressor ttgR; Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.
  • Length (amino acid): 210
  • Reference: Duque et al. 2001; Pubmed- 11251828, Teran et al. 2003; Pubmed- 14506010, Fernandes et al. 2003; Pubmed- 13678823

    		• Similar resistance genes in 'BacMet Predicted database'
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