BacMet Experimentally Confirmed database

Result: Details of the source of prediction- ymgB/ariR

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0450
  • Code for: Binding protein
  • Family: AriR family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Plasmid pPag3 (Pantoea vagans (strain C9-1) (Pantoea agglomerans (strain C9-1)))
  • Compound: Hydrochloric Acid (HCl) [class: Acid], Hydrogen Peroxide (H2O2) [class: Peroxides]
  • Description: Two-component-system connector protein YmgB/AriR; a connector protein for RcsB/C regulation of biofilm and acid-resistance, providing additional signal input into the two-component signaling pathway. May serve to stimulate biofilm maturation, via the Rcs phosphorelay. Regulates expression of genes involved in acid-resistance and biofilm formation, including the RcsB/C two-component system. May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition. Also confers resistance to H2O2. Overexpression at 28 and 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB; YmgB probably acts upstream of the RcsB/C system to stimulate the activity and not transcription of RcsB/C. 5-fluorouracil reduction in biofilm formation requires this protein. Deletion increases biofilm formation.
  • Length (amino acid): 88
  • Reference: Lee et al. 2007; Pubmed- 17765265

  • Similar resistance genes in 'BacMet Predicted database'

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