BacMet Experimentally Confirmed database

Result: Details of the source of prediction- qacA

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0319
  • Code for: Efflux
  • Family: Major facilitator superfamily (MFS)
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Only gram +ve, Staphylococcus aureus
  • Location: Plasmid VRSAp, pSK1 (S. Aureus)
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Chlorhexidine [class: Biguanides], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Crystal Violet [class: Triarylmethane], Pyronin Y [class: Xanthene], Quinaldine red [class: Quinolines], Rhodamine 6G [class: Xanthene], Safranin O [class: Azin], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Alexidine [class: Biguanides], Amicarbalide [class: Diamidine], Pentamidine [class: Diamidine], Hexamidine [class: Diamidine], Propamidine [class: Diamidine], Diamidinodiphenylamine [class: Diamidine], Dibrompropamidine [class: Diamidine], 1a-62/JC-1-127 [class: Guanylhydrazones], 1i-39/JC-1-134 [class: Guanylhydrazones], Stilbamidine [class: Diamidine], Phenamidine [class: Diamidine], Diminazene [class: Diamidine]
  • Description: Antiseptic resistnce gene qacA; Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines. qacA and qacB are different in sequence similarities by just by 7 nucleotides.
  • Length (amino acid): 514
  • Reference: Tennent et al 1989; Pubmed- 2778425, Rouch et al. 1990; Pubmed- 2089219, Paulsen et al. 1996; Pubmed- 8622987, Mitchell et al. 1998; Pubmed- 9527814

  • Similar resistance genes in 'BacMet Predicted database'

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