BacMet ID: BAC0498Code for: Regulator
Family: Contains 1 HTH dtxR-type DNA-binding domainSequence: FASTA
Cross-database IDs: Link
Organism: Mycobacterium tuberculosisLocation: Chromosome
Compound: Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides], Plumbagin [class: Naphthoquinone]Description: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism. Acts as a repressor of siderophore biosynthesis and as a Positive modulator of iron storage. Also regulates expression of transporters, proteins involved in siderophore synthesis, iron storage and transcriptional regulators. Has a role in oxidative streee tolerance.
Length (amino acid): 230
Reference: Rodriguez et al. 2002; Pubmed- 12065475
|Similar resistance genes in 'BacMet Predicted database'|