BacMet Experimentally Confirmed database

Result: Details of the source of prediction- ideR

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0498
  • Code for: Regulator
  • Family: Contains 1 HTH dtxR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Mycobacterium tuberculosis
  • Location: Chromosome
  • Compound: Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides], Plumbagin [class: Naphthoquinone]
  • Description: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism. Acts as a repressor of siderophore biosynthesis and as a Positive modulator of iron storage. Also regulates expression of transporters, proteins involved in siderophore synthesis, iron storage and transcriptional regulators. Has a role in oxidative streee tolerance.
  • Length (amino acid): 230
  • Reference: Rodriguez et al. 2002; Pubmed- 12065475

  • Similar resistance genes in 'BacMet Predicted database'

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