BacMet ID: BAC0196Code for: Regulator
Family: Contains 1 HTH iclR-type DNA-binding domain, 1 iclR-ED (iclR effector binding) domainSequence: FASTA
Cross-database IDs: Link
Organism: Escherichia coli (strain K12)Location: Chromosome
Compound: Sodium acetate [class: Acetate]Description: Acetate operon repressor; Regulation of the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase as well as isocitrate dehydrogenase kinase/phosphorylase. Glyoxylate disrupts the interaction with the promoter by favoring the inactive dimeric form. Pyruvate enhances promoter binding by stabilizing the tetrameric form.
Length (amino acid): 274
Reference: Spencer et al. 2007; Pubmed- 17238290, Sunnarborg et al. 1990; Pubmed- 2185227
|Similar resistance genes in 'BacMet Predicted database'|