BacMet Experimentally Confirmed database

Result: Details of the source of prediction- iclR

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0196
  • Code for: Regulator
  • Family: Contains 1 HTH iclR-type DNA-binding domain, 1 iclR-ED (iclR effector binding) domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium acetate [class: Acetate]
  • Description: Acetate operon repressor; Regulation of the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase as well as isocitrate dehydrogenase kinase/phosphorylase. Glyoxylate disrupts the interaction with the promoter by favoring the inactive dimeric form. Pyruvate enhances promoter binding by stabilizing the tetrameric form.
  • Length (amino acid): 274
  • Reference: Spencer et al. 2007; Pubmed- 17238290, Sunnarborg et al. 1990; Pubmed- 2185227

  • Similar resistance genes in 'BacMet Predicted database'

    BacMet database and website is designed and maintained by Chandan Pal

    Copyright © 2013 All rights reserved

    GU logo