BacMet Experimentally Confirmed database

Result: Details of the source of prediction- hefA

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0187
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Helicobacter pylori (strain P12)
  • Location: Chromosome
  • Compound: Hydrochloric acid (HCl) [class: Acid]
  • Description: Outer-membrane protein of the HefABC efflux system HefA; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA
  • Length (amino acid): 477
  • Reference: Liu et al. 2008; Pubmed- 18777600

  • Similar resistance genes in 'BacMet Predicted database'

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