BacMet Experimentally Confirmed database

Result: Details of the source of prediction- hdeA/yhiB

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0185
  • Code for: Chaperone
  • Family: HdeA family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Hydrochloric acid (HCl) [class: Acid]
  • Description: Acid stress chaperone HdeA; Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA
  • Length (amino acid): 110
  • Reference: Hong et al. 2005; Pubmed- 15911614

  • Similar resistance genes in 'BacMet Predicted database'

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