BacMet ID: BAC0177Code for: Regulator
Family: AraC familySequence: FASTA
Cross-database IDs: Link
Organism: Escherichia coli (strain K12)Location: Chromosome
Compound: Hydrochloric acid (HCl) [class: Acid], Rhodamine 6G [class: Xanthene], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]Description: Role in acid resistance, increases multidrug resistance in E. coli by activating the MdtEF multidrug efflux pump; Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA, gadB and gadC. Depending on the conditions (growth phase and medium), can repress gadW. It can confer resistance to antibiotics such as oxacillin, cloxacillin, nafcillin, erythromycin etc.
Length (amino acid): 274
Reference: Nishino et al. 2008; Pubmed- 18297445, Shin et al. 2001; Pubmed- 11555293
|Similar resistance genes in 'BacMet Predicted database'|