BacMet Experimentally Confirmed database

Result: Details of the source of prediction- gadX

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
gadX
  • BacMet ID: BAC0177
  • Code for: Regulator
  • Family: AraC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Hydrochloric acid (HCl) [class: Acid], Rhodamine 6G [class: Xanthene], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Role in acid resistance, increases multidrug resistance in E. coli by activating the MdtEF multidrug efflux pump; Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA, gadB and gadC. Depending on the conditions (growth phase and medium), can repress gadW. It can confer resistance to antibiotics such as oxacillin, cloxacillin, nafcillin, erythromycin etc.
  • Length (amino acid): 274
  • Reference: Nishino et al. 2008; Pubmed- 18297445, Shin et al. 2001; Pubmed- 11555293

  • Similar resistance genes in 'BacMet Predicted database'


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