BacMet Experimentally Confirmed database

Result: Details of the source of prediction- fabV

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0159
  • Code for: Enzyme
  • Family: short-chain dehydrogenases/reductases (SDR) family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio chloerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
  • Location: Chromosome
  • Compound: Triclosan [class: Phenolic compounds]
  • Description: Enoyl-(acyl-carrier-protein) (ACP) reductase is a key enzyme in type II fatty-acid synthases that catalyzes the last step in each elongation cycle; Predominately found in Vibrio species and closely related organisms where it seems to be the sole enoyl-ACP reductase. It is a antibacterial target site for triclosan where fabI and other isoforms such as fabL, fabI or fabK are absent. Triclosan expression of FabV in organism results in markedly increased resistance to triclosan. There may be bacteria that have both FabV and FabK such as various of the Clostridia such as Clostridium tetani.
  • Length (amino acid): 401
  • Reference: Massengo-Tiasse et al. 2008; Pubmed- 18032386, Zhu et al. 2010; Pubmed- 19933806,

  • Similar resistance genes in 'BacMet Predicted database'

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