BacMet Experimentally Confirmed database

Result: Details of the source of prediction- fabL/ygaA

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0158
  • Code for: Enzyme
  • Family: short-chain dehydrogenases/reductases (SDR) family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus subtilis (strain 168)
  • Location: Chromosome
  • Compound: Triclosan [class: Phenolic compounds]
  • Description: Enoyl-(acyl-carrier-protein) reductase (NADPH) FabL; It catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistance to triclosan. It is an alternative target site where fabI is absent for antibacterial compound triclosan.
  • Length (amino acid): 250
  • Reference: Heath et al. 2000; Pubmed- 11007778

  • Similar resistance genes in 'BacMet Predicted database'

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