BacMet ID: BAC0158Code for: Enzyme
Family: short-chain dehydrogenases/reductases (SDR) family.Sequence: FASTA
Cross-database IDs: Link
Organism: Bacillus subtilis (strain 168)Location: Chromosome
Compound: Triclosan [class: Phenolic compounds]Description: Enoyl-(acyl-carrier-protein) reductase (NADPH) FabL; It catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistance to triclosan. It is an alternative target site where fabI is absent for antibacterial compound triclosan.
Length (amino acid): 250
Reference: Heath et al. 2000; Pubmed- 11007778
|Similar resistance genes in 'BacMet Predicted database'|