emrBsm | BacMet ID: BAC0500Code for: Efflux
Family: MFS superfamilySequence: FASTA
Cross-database IDs: Link
Organism: Stenotrophomonas maltophilia (strain K279a)Location: Chromosome
Compound: Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide]Description: Part of EmrCABsm efflux pump which is a similar pump found in E. coli (EmrCAB) with below 50% amino acid identities. EmrCsm and EmrAB are essential for the function of the EmrCABsm pump. EmrCABsm pump may have a physiological role in evading naturally produced molecules from the environment or host-derived compounds, rather than in antimicrobial extrusion, allowing S. maltophilia to survive in its ecological niche. It can confer resistance to hydrophobic antibiotics nalidixic acid and erythromycin.
Length (amino acid): 528
Reference: Huang et al. 2013; Pubmed- 23794602
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Similar resistance genes in 'BacMet Predicted database' |