BacMet ID: BAC0499Code for: Efflux
Family: MFS superfamilySequence: FASTA
Cross-database IDs: Link
Organism: Stenotrophomonas maltophilia (strain K279a)Location: Chromosome
Compound: Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) [class: Hydrazone], Tetrachlorosalicylanilide (TCS) [class: Salicylanilide]Description: Part of EmrCABsm efflux pump which is a similar pump found in E. coli (EmrCAB) with below 50% amino acid identities. EmrCsm and EmrAB are essential for the function of the EmrCABsm pump. EmrCABsm pump may have a physiological role in evading naturally produced molecules from the environment or host-derived compounds, rather than in antimicrobial extrusion, allowing S. maltophilia to survive in its ecological niche. It can confer resistance to hydrophobic antibiotics nalidixic acid and erythromycin.
Length (amino acid): 393
Reference: Huang et al. 2013; Pubmed- 23794602
|Similar resistance genes in 'BacMet Predicted database'|