BacMet ID: BAC0138Code for: Enzyme
Family: Thioredoxin family. DsbC subfamilySequence: FASTA
Cross-database IDs: Link
Organism: Escherichia coli (strain K12)Location: Chromosome
Compound: Copper (Cu)Description: Disulfide isomerase; DsbC rearranges incorrect disulfide bonds formed by dsbA during oxidative protein folding under non-stress conditions. DsbC, a periplasmic thiol-disulfide oxidoreductase, appears to function as a disulfide isomerase both in vitro and in vivo. In vitro, DsbC has been shown to rearrange non-native disulfides in well studied isomerization substrates such as BPTI and RNase A. In vivo, DsbC is required for full activity of a handful of proteins containing at least one non-consecutive disulfide bond.
Length (amino acid): 236
Reference: Hiniker et al. 2005; Pubmed- 16087673
|Similar resistance genes in 'BacMet Predicted database'|