BacMet Experimentally Confirmed database

Result: Details of the source of prediction- dsbC

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0138
  • Code for: Enzyme
  • Family: Thioredoxin family. DsbC subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Copper (Cu)
  • Description: Disulfide isomerase; DsbC rearranges incorrect disulfide bonds formed by dsbA during oxidative protein folding under non-stress conditions. DsbC, a periplasmic thiol-disulfide oxidoreductase, appears to function as a disulfide isomerase both in vitro and in vivo. In vitro, DsbC has been shown to rearrange non-native disulfides in well studied isomerization substrates such as BPTI and RNase A. In vivo, DsbC is required for full activity of a handful of proteins containing at least one non-consecutive disulfide bond.
  • Length (amino acid): 236
  • Reference: Hiniker et al. 2005; Pubmed- 16087673

  • Similar resistance genes in 'BacMet Predicted database'

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