BacMet Experimentally Confirmed database

Result: Details of the source of prediction- cpxA

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0532
  • Code for: Regulator
  • Family: Contains 1 histidine kinase domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
  • Location: Chromosome
  • Compound: Hydrogen Peroxide (H2O2) [class: Peroxides], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides]
  • Description: Sensor protein of stress-related two-component regulatory system of CpxAR. It has role in oxidative stress tolerance. It has a regulatory role on MDR efflux pumps. It can confer resistance to cefepime, cefotaxime, ceftazidime and chloramphenicol which possibly are the preferred substrates of the resistance determinants for e.g. efflux pumps perhaps regulated by the Cpx regulon.
  • Length (amino acid): 457
  • Reference: Srinivasan et al. 2012; Pubmed- 22496764

  • Similar resistance genes in 'BacMet Predicted database'

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