BacMet ID: BAC0005Code for: Efflux
Family: RND superfamily, MFP familySequence: FASTA
Cross-database IDs: Link
Organism: Escherichia coli (strain K12)Location: Chromosome
Compound: Acriflavine [class: Acridine], Phenol [class: Phenolic compounds], Triclosan [class: Phenolic compounds], p-xylene [class: Aromatic hydrocarbons], Cyclohexane [class: Cycloalkane], Pentane [class: Alkane]Description: AcrAB is a drug efflux protein with a broad substrate specificity. It can confer resistant to ampicillin, chloramphenicol as well. It requires TolC outer memberane protein to function and form the AcrAB-TolC efflux operon. AcrAB-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates.
Length (amino acid): 397
Reference: Ma et al. 1993; Pubmed- 8407802, Ma et al. 1995; Pubmed- 7651136, White et al. 1997; Pubmed- 9324261, Aono et al. 1998, Pubmed- 9473050, Fralick et al. 1996; Pubmed- 8824631
|Similar resistance genes in 'BacMet Predicted database'|