BacMet Experimentally Confirmed database

Result: Details of the source of prediction- phoB

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
phoB
  • BacMet ID: BAC0530
  • Code for: Regulator
  • Family: Contains 1 histidine kinase domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae NTUH-K2044
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides]
  • Description: Part of the two-component regulatory system PhoBR. It regulates kpnO in K. pneumoniae. It has a role in role in capsule production and bacterial growth in K. pneumoniae. It has no role in oxidative stress tolerance and nitrostative stress tolernace, but in gastrointestinal like challenges. (NB: THIS GENE IS MORE LIKELY TO BE 'PhoP' THOUGH AUTHORS MENTIONED IT AS 'PhoB'. THE SYSTEM MIGHT BE 'PhoPQ' INSTEAD OF 'PhoBR'.)
  • Length (amino acid): 237
  • Reference: Srinivasan et al. 2012; Pubmed- 22848515

  • Similar resistance genes in 'BacMet Predicted database'


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