BacMet Experimentally Confirmed database

Result: Details of the source of prediction- merB

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
merB
  • BacMet ID: BAC0657
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas sp. K-62
  • Location: Plasmid pMR26
  • Compound: Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury], Methylmercury Acetate [class: Organo-mercury]
  • Description: MerB, encodes the enzyme organomercural lyase that breaks the carbon-mercury bond in toxic substrates such as phenymercury acetate; in gram negative it is rare, need for organomercural resistance.
  • Length (amino acid): 212
  • Reference: Kiyono et al. 1997; Pubmed- 9168120

    		• Similar resistance genes in 'BacMet Predicted database'
    merB
  • BacMet ID: BAC0658
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus aureus
  • Location: plasmid pI258
  • Compound: Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury]
  • Description: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg2+, which is subsequently detoxified by the mercuric reductase.
  • Length (amino acid): 216
  • Reference: Babich et al. 1991; Pubmed- 1954576, Laddaga et al. 1987; Pubmed- 3037534

    		• Similar resistance genes in 'BacMet Predicted database'
    merB
  • BacMet ID: BAC0659
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Serratia marcescens
  • Location: Plasmid pDU1358
  • Compound: Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury]
  • Description: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg2+, which is subsequently detoxified by the mercuric reductase.
  • Length (amino acid): 212
  • Reference: Griffin et al. 1987; Pubmed- 3033633,

    		• Similar resistance genes in 'BacMet Predicted database'
    merB
  • BacMet ID: BAC0660
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas stutzeri
  • Location: Plasmid pPB
  • Compound: Mercury (Hg)
  • Description: MerB, encodes the enzyme organomercural lyase that breaks the carbon-mercury bond in toxic substrates such as phenymercury acetate; in gram negative it is rare, need for organomercural resistance.
  • Length (amino acid): 219
  • Reference: Reniero et al. 1995; Pubmed- 8529897, Reniero et al. 1998; Pubmed- 9479042

    		• Similar resistance genes in 'BacMet Predicted database'
    merB1
  • BacMet ID: BAC0654
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus sp. (strain RC607)
  • Location: Chromosome
  • Compound: Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury]
  • Description: MerB of the first mer operon. MerB1, encodes the enzyme organomercural lyase that breaks the carbon-mercury bond in toxic substrates such as phenymercury acetate; in gram negative it is rare, need for organomercural resistance.
  • Length (amino acid): 218
  • Reference: Gupta et al. 1999; Pubmed- 10559175

    		• Similar resistance genes in 'BacMet Predicted database'
    merB1
  • BacMet ID: BAC0663
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus megaterium MB1
  • Location: Chromosome, Transposon TnMERI1
  • Compound: Mercury (Hg), Fluorescein mercuric acetate [class: Organo-mercury], p-chloro-mercuribenzoic acid [class: Organo-mercury], Phenylmercury Acetate [class: Organo-mercury]
  • Description: Fragment of merB1. Organomercurial lyase merB (merB1) is part of the first mer operon of the transposon TnMERI1 of Bacillus megaterium MB1.
  • Length (amino acid): 214
  • Reference: Huang et al. 1999; Pubmed- 10548738

    		• Similar resistance genes in 'BacMet Predicted database'
    merB2
  • BacMet ID: BAC0655
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus sp. (strain RC607)
  • Location: Chromosome
  • Compound: Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury]
  • Description: MerB of the second mer operon. MerB2, encodes the enzyme organomercural lyase that breaks the carbon-mercury bond in toxic substrates such as phenymercury acetate; in gram negative it is rare, need for organomercural resistance.
  • Length (amino acid): 209
  • Reference: Gupta et al. 1999; Pubmed- 10559175

    		• Similar resistance genes in 'BacMet Predicted database'
    merB2
  • BacMet ID: BAC0661
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus megaterium MB1
  • Location: Chromosome, Transposon TnMERI1
  • Compound: Mercury (Hg), Fluorescein mercuric acetate [class: Organo-mercury], p-chloro-mercuribenzoic acid [class: Organo-mercury], Phenylmercury Acetate [class: Organo-mercury]
  • Description: Organomercurial lyase merB (merB2) is part of the second mer operon of the transposon TnMERI1 of Bacillus megaterium MB1. This second MerB (MerB2: organomercurial lyse) contributes to confer resistance to a wide range of organomercuric compounds than presence of one merB.
  • Length (amino acid): 209
  • Reference: Huang et al. 1999; Pubmed- 10548738

    		• Similar resistance genes in 'BacMet Predicted database'
    merB3
  • BacMet ID: BAC0656
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus sp. (strain RC607)
  • Location: Chromosome
  • Compound: Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury]
  • Description: MerB of the third mer operon. MerB3, encodes the enzyme organomercural lyase that breaks the carbon-mercury bond in toxic substrates such as phenymercury acetate; in gram negative it is rare, need for organomercural resistance.
  • Length (amino acid): 218
  • Reference: Gupta et al. 1999; Pubmed- 10559175

    		• Similar resistance genes in 'BacMet Predicted database'
    merB3
  • BacMet ID: BAC0662
  • Code for: Enzyme
  • Family: MerB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus megaterium MB1
  • Location: Chromosome, Transposon TnMERI1
  • Compound: Mercury (Hg), Fluorescein mercuric acetate [class: Organo-mercury], p-chloro-mercuribenzoic acid [class: Organo-mercury], Phenylmercury Acetate [class: Organo-mercury], Thimerosal [class: Organo-mercury], Methylmercury chloride [class: Organo-mercury], Ethylmercury chloride [class: Organo-mercury]
  • Description: Organomercurial lyase merB (merB2) is part of the second mer operon of the transposon TnMERI1 of Bacillus megaterium MB1. This third MerB (MerB3: organomercurial lyse) contributes to confer resistance to a wide range of organomercuric compounds than presence of one merB.
  • Length (amino acid): 242
  • Reference: Huang et al. 1999; Pubmed- 10548738

    		• Similar resistance genes in 'BacMet Predicted database'

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