BacMet Database

Result: Details of the source of prediction- hdeA/yhiB

Gene_name	Experimentally Verified Resistance Gene Information	Predicted Resistance Gene Information
hdeA/yhiB	BacMet ID: BAC0185 Code for: Chaperone Family: HdeA family Sequence: FASTA Cross-database IDs: Link Organism: Escherichia coli (strain K12) Location: Chromosome Compound: Hydrochloric acid (HCl) [class: Acid] Description: Acid stress chaperone HdeA; Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA Length (amino acid): 110 Reference: Hong et al. 2005; Pubmed- 15911614	Similar resistance genes in 'BacMet Predicted database'

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