Browsing Experimentally Confirmed database

Result: Your query found 13 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
ttgA
  • BacMet ID: BAC0404
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: Toluene efflux pump periplasmic linker protein TtgA; The periplasmic linker protein component of a constitutive organic solvent efflux system ttgABC. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also Exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
  • Length (amino acid): 384
  • Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgB
  • BacMet ID: BAC0405
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The inner membrane transporter component, ttgB of a constitutive organic solvent efflux system ttgABC. Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also Exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
  • Length (amino acid): 1050
  • Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgC
  • BacMet ID: BAC0406
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The outer membrane component ttgC of a constitutive organic solvent efflux system ttgABC. Is involved in Export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene. Also exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
  • Length (amino acid): 484
  • Reference: Ramos et al. 1998; Pubmed- 9642183, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgD
  • BacMet ID: BAC0407
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes]
  • Description: The periplasmic linker protein component, ttgD of an inducible organic solvent efflux pump ttgDEF. Involved in export of toluene and styrene but not of m-xylene, propylbenzene or ethylbenzene. Is not involved in antibiotic or AMP efflux
  • Length (amino acid): 382
  • Reference: Mosqueda et al. 2000; Pubmed- 10648517, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgE
  • BacMet ID: BAC0408
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes]
  • Description: The inner membrane transporter component, ttgE of an inducible organic solvent efflux pump ttgDEF. Involved in export of toluene and styrene but not of m-xylene, propylbenzene or ethylbenzene. Is not involved in antibiotic or AMP efflux.
  • Length (amino acid): 1046
  • Reference: Mosqueda et al. 2000; Pubmed- 10648517, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgF
  • BacMet ID: BAC0409
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes]
  • Description: The outer membrane component, ttgF of an inducible organic solvent efflux pump ttgDEF. Involved in export of toluene and styrene but not of m-xylene, propylbenzene or ethylbenzene. Is not involved in antibiotic or AMP efflux.
  • Length (amino acid): 480
  • Reference: Mosqueda et al. 2000; Pubmed- 10648517, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgG
  • BacMet ID: BAC0410
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The periplasmic linker component ttgG, of an organic solvent efflux pump ttgGHI. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can Export AMP and some antibiotics.
  • Length (amino acid): 391
  • Reference: Rojas et al. 2001; Pubmed- 11395460, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgH
  • BacMet ID: BAC0411
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The inner membrane transporter component, ttgH of an organic solvent efflux pump ttgGHI. Involved in Export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can Export AMP and some antibiotics
  • Length (amino acid): 1049
  • Reference: Rojas et al. 2001; Pubmed- 11395460, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgI
  • BacMet ID: BAC0412
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: The outer membrane component, ttgI of an organic solvent efflux pump ttgGHI. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can Export AMP and some antibiotics.
  • Length (amino acid): 470
  • Reference: Rojas et al. 2001; Pubmed- 11395460, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgR
  • BacMet ID: BAC0413
  • Code for: Regulator
  • Family: Contains 1 HTH tetR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: n-hexane [class: Alkane], Toluene [class: Aromatic hydrocarbons], Dimethylphthalate [class: Pthalate], Styrene [class: Polystyrenes], m-xylene [class: Aromatic hydrocarbons], Ethylbenzene [class: Aromatic hydrocarbons], Propylbenzene [class: Aromatic hydrocarbons]
  • Description: Toluene efflux pump ttgABC operon repressor ttgR; Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.
  • Length (amino acid): 210
  • Reference: Duque et al. 2001; Pubmed- 11251828, Teran et al. 2003; Pubmed- 14506010, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgT
  • BacMet ID: BAC0414
  • Code for: Regulator
  • Family: Contains 1 HTH iclR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Chromosome
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes]
  • Description: Regulator of the ttgDEF efflux pump ttgT; Can regulate the ttgDEF system expression in ttgV-deficient condition; effect of TtgT on ttgGHI Expression is not obvious when TtgV is present but becomes relevant in its absence
  • Length (amino acid): 260
  • Reference: Teran et al. 2007; Pubmed- 17986203, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'
    ttgV
  • BacMet ID: BAC0415
  • Code for: Regulator
  • Family: Isocitrate lyase regulator (IclR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes]
  • Description: HTH-type transcriptional regulator TtgV; Represses the expression of the ttgGHI and ttgVW operons. Binds to the ttgGHI / ttgVW intergenic region, probably preventing binding of RNA polymerase; ttgV dissociates from this region in the presence of 1-hexanol, can regulate the ttgDEF expression as well; The ttgVW operon is induced by toluene and styrene, but not by the antibiotics carbenicillin, chloramphenicol, nalidixic acid, tetracycline or gentamicin
  • Length (amino acid): 259
  • Reference: Teran et al. 2007; Pubmed- 17986203, Rojas et al. 2003; Pubmed- 12896994, Rodriguez-Herva et al. 2007; Pubmed- 17504492

  • Similar resistance genes in 'BacMet Predicted database'
    ttgW
  • BacMet ID: BAC0416
  • Code for: Regulator
  • Family: Contains 1 HTH tetR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida (Arthrobacter siderocapsulatus)
  • Location: Plasmid pGRT1 (Pseudomonas putida (Arthrobacter siderocapsulatus))
  • Compound: Toluene [class: Aromatic hydrocarbons], Styrene [class: Polystyrenes]
  • Description: HTH-type transcriptional regulator TtgW; does not seem to be involved in regulation of the ttgGHI or ttgVW operons; The ttgVW operon is induced by toluene and styrene, but not by the antibiotics carbenicillin, chloramphenicol, nalidixic acid, tetracycline or gentamicin
  • Length (amino acid): 134
  • Reference: Rojas et al. 2003; Pubmed- 12896994, Fernandes et al. 2003; Pubmed- 13678823

  • Similar resistance genes in 'BacMet Predicted database'

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