Gene_name | Experimentally Verified Resistance Gene Information | Predicted Resistance Gene Information |
PA0320 | BacMet ID: BAC0297Code for:
UnknownFamily: Bacterial OB fold (BOF) protein familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Location:
ChromosomeCompound: Cadmium (Cd), Mercury (Hg), Tributyltin (TBT) [class: Organo-tin], Hydrogen Peroxide (H2O2) [class: Peroxides], Hydrochloric acid (HCl) [class: Acid]Description: TBT resistance gene PA0320; homologous to YgiW; PA0320 plays a certain role in stress tolerance against TBT as well as in stressors producing reactive oxygen speciesLength (amino acid):
116Reference: Fukushima et al. 2012; Pubmed- 22990488
| Similar
resistance genes in 'BacMet Predicted database' |
tbtA | BacMet ID: BAC0379Code for:
EffluxFamily: RND superfamily, MFP familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas stutzeri (Pseudomonas perfectomarina)Location:
ChromosomeCompound: Tributyltin (TBT) [class: Organo-tin], n-hexane [class: Alkane]Description: Tributyltin chloride resistance membrane fusion protein TbtA; has 4 characteristic motifs A, B, C and D; part of the tbtABM efflux systemLength (amino acid):
382Reference: Fukagawa et al. 1993; Pubmed- 8343157, Jude et al. 2004; Pubmed- 15019728
| Similar
resistance genes in 'BacMet Predicted database' |
tbtB | BacMet ID: BAC0380Code for:
EffluxFamily: RND superfamily, AcrB/AcrD/AcrF familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas stutzeri (Pseudomonas perfectomarina)Location:
ChromosomeCompound: Tributyltin (TBT) [class: Organo-tin], n-hexane [class: Alkane]Description: Resistance nodulation cell division family member TbtB; Aanalogous to proton dependent efflux pump belonging to RND family; part of the tbtABM efflux systemLength (amino acid):
1046Reference: Fukagawa et al. 1993; Pubmed- 8343157, Jude et al. 2004; Pubmed- 15019728
| Similar
resistance genes in 'BacMet Predicted database' |
tbtM | BacMet ID: BAC0381Code for:
EffluxFamily: RND Superfamily, OMP familySequence: FASTACross-database IDs: LinkOrganism: Pseudomonas stutzeriLocation:
ChromosomeCompound: Tributyltin (TBT) [class: Organo-tin], n-hexane [class: Alkane]Description: Outer membrane protein TbtM, part of the tbtABM efflux systemLength (amino acid):
476Reference: Fukagawa et al. 1993; Pubmed- 8343157, Jude et al. 2004; Pubmed- 15019728
| Similar
resistance genes in 'BacMet Predicted database' |
tbtR | BacMet ID: BAC0382Code for:
RegulatorFamily: Contains 1 HTH iclR-type DNA-binding domainSequence: FASTACross-database IDs: LinkOrganism: Pseudomonas stutzeri Location:
ChromosomeCompound: Tributyltin (TBT) [class: Organo-tin], n-hexane [class: Alkane]Description: Efflux pump regulator; a potential regulatory gene of tbtABM, named tbtR, is identified upstream of the operon; TbtR exhibited many similarities with other repressors of the RND efflux systemsLength (amino acid):
259Reference: Fukagawa et al. 1993; Pubmed- 8343157, Jude et al. 2004; Pubmed- 15019728
| Similar
resistance genes in 'BacMet Predicted database' |
ygiW | BacMet ID: BAC0445Code for:
UnknownFamily: Bacterial OB fold (BOF) protein familySequence: FASTACross-database IDs: LinkOrganism: Escherichia coliLocation:
Plasmid pMR-1 (Shewanella oneidensis (strain MR-1))Compound: Cadmium (Cd), Tributyltin (TBT) [class: Organo-tin], Hydrogen Peroxide (H2O2) [class: Peroxides]Description: Protein YgiW; located in periplasm; responsible for tributyltin (TBT) resistance; response to hydrogen peroxide (H2O2), cadmium ions ; has a role in biofim formationLength (amino acid):
130Reference: Lee et al. 2010; Pubmed- 19919618
| Similar
resistance genes in 'BacMet Predicted database' |