BacMet Experimentally Confirmed database

Result: Details of the source of prediction- smtA

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
smtA
  • BacMet ID: BAC0365
  • Code for: Binding protein
  • Family: Metallothionein superfamily. Type 14 family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Cyanobacteria (e.g. Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)); Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Zinc (Zn), Mercury (Hg)
  • Description: Metallothionein SmtA; Contain 9 cysteine residues; plays a role in essential metal ion homeostasis (especially zinc homeostasis) and resistance to certain non-essential metal ions. Metallothioneins have a high content of cysteine residues that bind various heavy metals. Cells that lack of metallothionein have reduced uptake of Zn++ and reduced tolerance to high Zn++ concentrations (althogh the Cu++ and Hg++ tolerances are unchanged); often Cd++ resistant when cells grow in high level of Cd++.
  • Length (amino acid): 56
  • Reference: Shi et al. 1992, Pubmed- 1607014

  • Similar resistance genes in 'BacMet Predicted database'


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