BacMet Experimentally Confirmed database

Result: Details of the source of prediction- mymT

Gene_nameExperimentally Verified Resistance Gene Information Predicted Resistance Gene Information
  • BacMet ID: BAC0262
  • Code for: Binding protein
  • Family: Metallothionein superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Mycobacterium tuberculosis
  • Location: Chromosome
  • Compound: Copper (Cu), Nickel (Ni), Zinc (Zn)
  • Description: Cu(I)-binding metallothionein mymT; Metallothioneins are small proteins that have a high content of cysteine residues wich allow them to bind heavy metal ions through clusters of thiolate bonds. MymT binds up to seven ions of Cu+, with a preference for four to six Cu+ ions, in a solvent-shielded core. MymT protects M. tuberculosis from copper toxicity. Up-regulated by copper, cadmium, cobalt, nickel and zinc, but not manganese.
  • Length (amino acid): 53
  • Reference: Gold et al. 2011; Pubmed- 18724363, Festa et al. 2011; Pubmed- 21166899

  • Similar resistance genes in 'BacMet Predicted database'

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