BacMet Database

Result: Details of the source of prediction- mdtK/ydhE

Gene_name	Experimentally Verified Resistance Gene Information	Predicted Resistance Gene Information
mdtK/ydhE	BacMet ID: BAC0218 Code for: Efflux Family: MATE family, MdtK subfamily Sequence: FASTA Cross-database IDs: Link Organism: Escherichia coli (strain K12) Location: Chromosome Compound: Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine] Description: Multidrug resistance protein MdtK; It functions as a Na+/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin), tetraphenylphosphonium ion (TPP), deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, Acriflavine, ethidium bromide and benzylkonium Length (amino acid): 457 Reference: Nishino et al. 2001; Pubmed- 11566977	Similar resistance genes in 'BacMet Predicted database'

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