BacMet Database

Result: Details of the source of prediction- csoR

Gene_name	Experimentally Verified Resistance Gene Information	Predicted Resistance Gene Information
csoR	BacMet ID: BAC0558 Code for: Regulator Family: CsoR family Sequence: FASTA Cross-database IDs: Link Organism: Bacillus subtilis 168 Location: Chromosome Compound: Copper (Cu) Description: Copper-sensing transcriptional repressor CsoR. Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu1+, which significantly decreases its DNA binding affinity and leads to the transcription of the genes. Cells lacking this gene display a slightly enhanced ability to grow into medium containing high levels of copper. Length (amino acid): 101 Reference: Chillappagari et al. 2009; Pubmed- 19168619	Similar resistance genes in 'BacMet Predicted database'

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